Ketamine for Bipolar Disorder


- Bipolar disorder can cause depressive episodes that are similar to major depression and can last for weeks, months, or even years
- Clinical trials have demonstrated rapid antidepressant effects with intravenous (IV) ketamine for major depressive disorder, with relatively less research specifically for bipolar depression.
- Real-world effectiveness of IV ketamine for bipolar depression was observed. Repeated doses were associated with greater symptom reduction and adequate tolerability.

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