ketamine for fibromyalgia

---

• Bipolar disorder can cause depressive episodes that are similar to major depression and can last for weeks, months, or even years
• Clinical trials have demonstrated rapid antidepressant effects with intravenous (IV) ketamine for major depressive disorder, with relatively less research specifically for bipolar depression.
•  Real-world effectiveness of IV ketamine for bipolar depression was observed. Repeated doses were associated with greater symptom reduction and adequate tolerability.
• 
  

Fancy F, Rodrigues NB, Di Vincenzo JD, Chau EH, Sethi R, Husain MI, Gill H, Tabassum A, Mckenzie A, Phan L, McIntyre RS, Rosenblat JD. Real-world effectiveness of repeated ketamine infusions for treatment-resistant bipolar depression. Bipolar Disord. 2023 Mar;25(2):99-109. doi: 10.1111/bdi.13284. Epub 2022 Dec 26. PMID: 36516343.