ketamine for ocd

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• The obsessive-compulsive spectrum refers to disorders drawn from several diagnostic categories that share core features related to obsessive-compulsive disorder (OCD), such as obsessive thoughts, compulsive behaviors and anxiety.
• According to the literature [3,40,55], ketamine via IV infusion significantly improves obsessive–compulsive symptomatology, with effects that are rapid (occurring in hours to minutes).
• The anti-obsessional effects of ketamine and NMDA receptor antagonists do show therapeutic potential.

Martinotti G, Chiappini S, Pettorruso M, Mosca A, Miuli A, Di Carlo F, D'Andrea G, Collevecchio R, Di Muzio I, Sensi SL, Di Giannantonio M. Therapeutic Potentials of Ketamine and Esketamine in Obsessive-Compulsive Disorder (OCD), Substance Use Disorders (SUD) and Eating Disorders (ED): A Review of the Current Literature. Brain Sci. 2021 Jun 27;11(7):856. doi: 10.3390/brainsci11070856. PMID: 34199023; PMCID: PMC8301752.